Invitrogen

EphB4 Recombinant Rabbit Monoclonal Antibody (K01_3L82)

Name: EphB4 Recombinant Rabbit Monoclonal Antibody (K01_3L82)
Brand: Invitrogen
SKU: MA564406

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说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (3)

EphB4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 3

EphB4 Antibody (MA564406) in IHC (P)

Immunohistochemistry (Paraffin) analysis of EphB4 in paraffin-embedded Human breast cancer tissue. Samples were incubated with EphB4 recombinant monoclonal (Product # MA564406). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Immunogen image

Immunogen Image EphB4 Recombinant Rabbit Monoclonal Antibody (K01_3L82)

产品信息

MA564406

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:100

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

K01_3L82

抗原

Recombinant protein of human Eph receptor B4/HTK (aa 17-529).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

50mM tris glycine, pH 7.4, with 40% glycerol, 0.05% BSA, 150mM NaCl

内含物

0.01% sodium azide

保存条件

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_3705454

产品详细信息

Immunogen sequence: EETLLNTKLE TADLKWVTFP QVDGQWEELS GLDEEQHSVR TYEVCDVQRA PGQAHWLRTG WVPRRGAVHV YATLRFTMLE CLSLPRAGRS CKETFTVFYY ESDADTATAL TPAWMENPYI KVDTVAAEHL TRKRPGAEAT GKVNVKTLRL GPLSKAGFYL AFQDQGACMA LLSLHLFYKK CAQLTVNLTR FPETVPRELV VPVAGSCVVD AVPAPGPSPS LYCREDGQWA EQPVTGCSCA PGFEAAEGNT KCRACAQGTF KPLSGEGSCQ PCPANSHSNT IGSAVCQCRV GYFRARTDPR GAPCTTPPSA PRSVVSRLNG SSLHLEWSAP LESGGREDLT YALRCRECRP GGSCAPCGGD LTFDPGPRDL VEPWVVVRGL RPDFTYTFEV TALNGVSSLA TGPVPFEPVN VTTDREVPPA VSDIRVTRSS PSSLSLAWAV PRAPSGAVLD YEVKYHEKGA EGPSSVRFLK TSENRAELRG LKRGASYLVQ VRARSEAGYG PFGQEHHSQT QLD

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 42%, Pig - 95%, Cynomolgus monkey - 100%.

靶标信息

EPHB4 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by EphB4 binds to ephrin-B2 and plays an essential role in vascular development.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Developmental kinase 2; EPH receptor B4; ephrin receptor EphB4; Ephrin type-B receptor 4; Hepatoma transmembrane kinase; mDK-2; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyrosine kinase MYK-1; tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase TYRO11

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基因别名: AI042935; EPHB4; HTK; MDK2; MYK1; TYRO11

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UniProt ID: (Human) P54760, (Mouse) P54761

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Entrez Gene ID: (Human) 2050, (Rat) 686310, (Mouse) 13846

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