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Fabgennix
Ephrin Receptor A7 Polyclonal Antibody, FITC
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产品信息
EPHAR7-FITC
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding taken within amino acid region 500-550 on human Ephrin type-A receptor 7 protein.
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
EPHA7 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA7 is involved in embryonic development. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Developmental kinase 1; EBK; EHK-3; EK11; Embryonic brain kinase; epa7; EPH homology kinase 3; Eph homology kinase-3; EPH-like kinase 11; EPHA7-S; ephrin receptor EphA7; Ephrin type-A receptor 7; mDK-1; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3
基因别名: Cek11; Ebk; EHK-3; EHK3; EK11; EPHA7; HEK11; Mdk1
UniProt ID: (Human) Q15375, (Rat) P54759, (Mouse) Q61772
Entrez Gene ID: (Human) 2045, (Rat) 171287, (Mouse) 13841
protein tyrosine kinase activity
GPI-linked ephrin receptor activity
protein binding
ATP binding
axon guidance receptor activity
chemorepellent activity
ephrin receptor binding
ephrin receptor activity
nucleotide binding
protein kinase activity
transmembrane receptor protein tyrosine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
positive regulation of protein phosphorylation
apoptotic process
brain development
phosphorylation
peptidyl-tyrosine phosphorylation
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
regulation of protein autophosphorylation
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of neuron apoptotic process
ephrin receptor signaling pathway
negative regulation of collateral sprouting
branching morphogenesis of a nerve
regulation of peptidyl-tyrosine phosphorylation
negative chemotaxis
negative regulation of synapse assembly
regulation of ERK1 and ERK2 cascade
nephric duct morphogenesis
signal transduction
positive regulation of apoptotic process
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
