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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • EphA8 Antibodies

          Fabgennix

          Ephrin Receptor A8 Polyclonal Antibody, Biotin

          查看其他10个EphA8抗体

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          Cite Ephrin Receptor A8 Polyclonal Antibody, Biotin

          产品信息

          EPHAR8-BIOTIN

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500-1:1,000
          -

          酶联免疫吸附实验 (ELISA)

          1:10,000
          -

          免疫沉淀 (IP)

          1:50-1:250
          -
          产品规格

          种属反应

          Human, Mouse

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          Synthetic peptide corresponding to unique amino acid sequences on human EphA R8 protein.

          偶联物

          Biotin Biotin Biotin

          形式

          Liquid

          浓度

          0.5-1.5 mg/mL

          纯化类型

          Affinity chromatography

          保存液

          proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

          内含物

          0.02% sodium azide

          保存条件

          -20°C

          运输条件

          Ambient (domestic); Wet ice (international)

          靶标信息

          EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA8 plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: EK3; epa8; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; EPH-like kinase 3; Ephrin type-A receptor 8; Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) (EPH-and ELK-related kinase); hydroxyaryl-protein kinase; protein-tyrosine kinase; Tyrosine-protein kinase receptor EEK; tyrosylprotein kinase

          查看更多 收起

          基因别名: AW047546; EEK; EK3; EPHA8; HEK3; KIAA1459; mKIAA1459

          查看更多 收起

          UniProt ID: (Human) P29322, (Mouse) O09127

          查看更多 收起

          Entrez Gene ID: (Human) 2046, (Mouse) 13842

          查看更多 收起

          功能
          GPI-linked ephrin receptor activity ATP binding nucleotide binding protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity ephrin receptor activity protein binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups transmembrane signal receptor
          参与通路
          substrate-dependent cell migration cell adhesion axon guidance neuron remodeling peptidyl-tyrosine phosphorylation regulation of cell adhesion neuron projection development regulation of cell adhesion mediated by integrin positive regulation of MAPK cascade positive regulation of phosphatidylinositol 3-kinase activity protein autophosphorylation ephrin receptor signaling pathway protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway multicellular organism development nervous system development phosphorylation
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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