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Invitrogen
Erenumab Recombinant Human Monoclonal Antibody
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产品信息
MA5-42108
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG2, lambda
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human CALCRL/CGRP-R
偶联物
形式
Liquid
浓度
1.12 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only FDA approved treatment specifically developed to prevent migraine by blocking the CGRP receptor, which is believed to play a critical role in migraine .
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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