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Invitrogen
Ethinylestradiol Polyclonal Antibody
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产品信息
PA1-75138
产品规格
种属反应
Chemical
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Ethinylestradiol(3)-BTG
偶联物
形式
Liquid
浓度
8.13 mg/mL
纯化类型
purified
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Working Concentration: 2.5 µg/mL. Sensitivity: 10 ng/mL Ethinyl Estradiol produces 86% inhibition in a competitive ELISA employing Ethinylestradiol polyclonal antibody.
靶标信息
Ethinyl Estradiol is a semisynthetic alkylated estradiol with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in oral contraceptives. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. [National Center for Biotechnology Information. PubChem Compound Database; CID=5991].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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