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Invitrogen
Evinacumab Recombinant Human Monoclonal Antibody
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产品信息
MA5-42049
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG4, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human ANGPTL3
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein A/G
保存液
30mM histidine/PBS, pH 5.8, with 262mM sucrose, 0.006% Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Evinacumab is a biosimilar that targets ANGPTL3. This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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