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Invitrogen
FA2H Polyclonal Antibody
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FIGURE: 1 / 5
FA2H Antibody (PA5-24728) in IHC (P)
Immunohistochemistry analysis of FA2H in formalin fixed and paraffin embedded brain tissue. Samples were incubated with FA2H polyclonal antibody (Product # PA5-24728) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-24728
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 121-148 amino acids from the central region of human FA2H
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Amount
160 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with non-human primate and rat based on sequence homology.
Target Information
FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; fatty acid hydroxylase domain containing 1; FLJ25287
Gene Aliases: Fa2h; FAAH; Faxdc1; G630055L08Rik
UniProt ID: (Mouse) Q5MPP0
Entrez Gene ID: (Mouse) 338521
iron ion binding
N-ethylmaleimide reductase activity
oxidoreductase activity
heme binding
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
metal ion binding
epoxyqueuosine reductase activity
fatty acid alpha-hydroxylase activity
hydroxylase
sebaceous gland cell differentiation
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
transport
lipid modification
central nervous system myelin maintenance
peripheral nervous system myelin maintenance
regulation of cell proliferation
regulation of hair cycle
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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