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Invitrogen
FABP4 Monoclonal Antibody (10E12)
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FABP4 Antibody (MA5-49201) in IHC (P)
Immunohistochemistry analysis of FABP4 in paraffin-embedded section of human gall bladder adenosquamous carcinoma tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with FABP4 Monoclonal antibody (Product # MA5-49201) using a dilution of 2 μg/mL overnight at 4°C. Biotinylated go... View More
产品信息
MA5-49201
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
10E12
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human FABP4 (10-40aa KLVSSENFDDYMKEVGVGFATRKVAGMAKPN).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Immunogen sequence is identical to the related mouse and rat sequences.
Positive Control - WB: human RT4 whole cell, human HL-60 whole cell, rat thymus tissue, mouse thymus tissue. IHC: human renal clear cell carcinoma tissue, human gall bladder adenosquamous carcinoma tissue, human gastric cancer tissue, human lymphadenoma tissue, rat intestines tissue, mouse intestines tissue, mouse intestines tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
FABP4 belongs to the fatty acid binding protein (FABP) family. FABPs contribute to the transport of fatty acids and other lipids in various cellular pathways. FABP4 is expressed in adipocytes, macrophages, monocyte-derived dendritic cells, and myoepithelial cells. It delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3T3-L1 lipid-binding protein; A-FABP; adipocyte fatty acid binding protein; Adipocyte lipid binding protein; Adipocyte lipid-binding protein; adipocyte protein aP2; Adipocyte-type fatty acid-binding protein; AFABP; ALBP; epididymis secretory protein Li 104; Fatty acid binding protein 4 adipocyte; fatty acid binding protein 4, adipocyte; Fatty acid-binding protein 4; Fatty acid-binding protein, adipocyte; HEL S 104; Myelin P2 protein homolog; P15; P2 adipocyte protein; Protein 422
基因别名: 422/aP2; A-FABP; AFABP; ALBP; ALBP/Ap2; Ap2; FABP4; HEL-S-104; Lbpl
UniProt ID: (Human) P15090, (Mouse) P04117
Entrez Gene ID: (Human) 2167, (Mouse) 11770, (Rat) 79451
cytokine production
negative regulation of protein kinase activity
transport
triglyceride catabolic process
cholesterol homeostasis
negative regulation of transcription, DNA-templated
positive regulation of inflammatory response
white fat cell differentiation
brown fat cell differentiation
cellular response to lithium ion
fatty acid metabolic process
positive regulation of cell proliferation
response to drug
response to glucocorticoid
