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Invitrogen
FAF1 Polyclonal Antibody
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产品信息
PA5-27687
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human FAF1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.66 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, NIH-3T3.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (87%), Xenopus laevis (91%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; hFAF1; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A
基因别名: AA408698; CGI-03; Dffrx; FAF1; Fam; hFAF1; HFAF1s; UBXD12; UBXN3A
UniProt ID: (Human) Q9UNN5, (Mouse) P54731
Entrez Gene ID: (Human) 11124, (Mouse) 14084
apoptotic process
cytoplasmic sequestering of NF-kappaB
cell death
positive regulation of cell death
regulation of cell adhesion
positive regulation of protein complex assembly
regulation of protein catabolic process
positive regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of protein kinase activity
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
