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Invitrogen
FAM122A Polyclonal Antibody
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产品信息
PA5-63338
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AQLSDPGVCV SSDTLDGNSS SAGSSCNSPA KVSTTTDSPV SPAQAASPFI PLDE
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 96%.
靶标信息
Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin- mediated proteolysis of WEE1, thereby releasing G2/M checkpoint.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PABIR family member 1; PPP2R1A-PPP2R2A-interacting phosphatase regulator 1
基因别名: C9orf42; FAM122A; PABIR1
UniProt ID: (Human) Q96E09
Entrez Gene ID: (Human) 116224
