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Invitrogen
FAM122A Monoclonal Antibody (3E9)
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FAM122A Antibody (MA5-24510) in WB
Western blot analysis of F122A / FAM122A in transfected 293T cell line. Lane 1: FAM122A transfected lysate (Predicted MW: 30.5 KDa). Lane 2: Non-transfected lysate. Samples were probed using a Mouse Monoclonal F122A / FAM122A (3E9) Antibody (Product # MA5-24510).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-24510
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3E9
抗原
FAM122A (NP_612206.3, 1 a.a. ~ 287 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide Sequence: MAQEKMELDL ELPPGTGGSP AEGGGSGGGG GLRRSNSAPL IHGLSDTSPV FQAEAPSARR NSTTFPSRHG LLLPASPVRM HSSRLHQIKQ EEGMDLINRE TVHEREVQTA MQISHSWEES FSLSDNDVEK SASPKRIDFI PVSPAPSPTR GIGKQCFSPS LQSFVSSNGL PPSPIPSPTT RFTTRRSQSP INCIRPSVLG PLKRKCEMET EYQPKRFFQG ITNMLSSDVA QLSDPGVCVS SDTLDGNSSS AGSSCNSPAK VSTTTDSPVS PAQAASPFIP LDELSSK
靶标信息
Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin- mediated proteolysis of WEE1, thereby releasing G2/M checkpoint.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: PABIR family member 1; PPP2R1A-PPP2R2A-interacting phosphatase regulator 1
基因别名: C9orf42; FAM122A; PABIR1
Entrez Gene ID: (Human) 116224
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