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Abnova
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSVGHKAQES KIRYKTNEPV WEENFTFFIH NPKRQDLEVE VRDEQHQCSL GNLKVPLSQL LTSEDMTVSQ RFQLSNSGPN STIKMKIALR VLHLEKRERP PDHQHSAQVK RPSVSKEGRK TSIKSHMSGS PGPGGSNTAP STPVIGGSDK PGMEEKAQPP EAGPQGLHDL GRSSSSLLAS PGHISVKEPT PSIASDISLP IATQELRQRL RQLENGTTLG QSPLGQIQLT IRHSSQRNKL IVVVHACRNL IAFSEDGSDP YVRMYLLPDK RRSGRRKTHV SKKTLNPVFD QSFDFSVSLP EVQRRTLDVA VKNSGGFLSK DKGLLGKVLV ALASEELAKG WTQWYDLTED GTRPQAMT
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:27044890). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Chr2Syt; E-Syt2; Extended synaptotagmin-2
基因别名: ESYT2; FAM62B; KIAA1228
Entrez Gene ID: (Human) 57488