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Abnova
FAM62B Monoclonal Antibody (1E10)
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产品信息
H00057488-M05
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1E10
抗原
FAM62B (AAH13957, 1 a.a. approximately 358 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: MSVGHKAQES KIRYKTNEPV WEENFTFFIH NPKRQDLEVE VRDEQHQCSL GNLKVPLSQL LTSEDMTVSQ RFQLSNSGPN STIKMKIALR VLHLEKRERP PDHQHSAQVK RPSVSKEGRK TSIKSHMSGS PGPGGSNTAP STPVIGGSDK PGMEEKAQPP EAGPQGLHDL GRSSSSLLAS PGHISVKEPT PSIASDISLP IATQELRQRL RQLENGTTLG QSPLGQIQLT IRHSSQRNKL IVVVHACRNL IAFSEDGSDP YVRMYLLPDK RRSGRRKTHV SKKTLNPVFD QSFDFSVSLP EVQRRTLDVA VKNSGGFLSK DKGLLGKVLV ALASEELAKG WTQWYDLTED GTRPQAMT
靶标信息
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:27044890). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chr2 synaptotagmin; Chr2Syt; E-Syt2; extended synaptotagmin like protein 2; extended synaptotagmin protein 2; Extended synaptotagmin-2; extended synaptotagmin-like protein 2; family with sequence similarity 62 (C2 domain containing), member B
基因别名: CHR2SYT; E-Syt2; ESYT2; FAM62B; KIAA1228
UniProt ID: (Human) A0FGR8
Entrez Gene ID: (Human) 57488
