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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: HALESFSFLN EDEDEDNDVP GDRPPSSPEA GAEDSIDSPS ARPLSTGCPA LDAALVRHLY HCSRLLLKLG TFGPLRCQEA WALERLLREA RVLEAVCEFS RRWEIPASSA QEVVQFS
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.
Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ13725; Rho family-interacting cell polarization regulator 1
基因别名: FAM65A; KIAA1930; RIPOR1
Entrez Gene ID: (Human) 79567