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Invitrogen
FAM73A Polyclonal Antibody
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产品信息
PA5-32001
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human FAM73A. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The FAM73A gene, also known as Family With Sequence Similarity 73 Member A, is located on chromosome 2q33.3. This gene encodes a protein embedded in cellular membranes and is recognized for its involvement in various cellular processes including signal transduction and cell communication. FAM73A has been observed to play a significant role in the regulation of cancer stem cell-like properties, particularly in gastric cancer, where its circular RNA form (circFAM73A) has been implicated in tumor progression. Additionally, FAM73A is involved in iron homeostasis and resistance mechanisms within the cell, suggesting its participation in broader metabolic and stress response pathways. The gene includes multiple exons and is subject to alternative splicing, which yields various transcript variants, enhancing its functional diversity within different cellular contexts.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: family with sequence similarity 73 member A; family with sequence similarity 73, member A; Mitoguardin 1; Protein FAM73A
基因别名: FAM73A; MIGA1
UniProt ID: (Human) Q8NAN2
Entrez Gene ID: (Human) 374986
