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Recommended positive controls: HCT116.
Predicted reactivity: Mouse (89%), Rat (85%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CSX-associated LIM; FBLP-1; Filamin-binding LIM protein 1; filamin-binding LIM protein-1; MIG2-interacting protein; Migfilin; mitogen-inducible 2 interacting protein; Mitogen-inducible 2-interacting protein
基因别名: CAL; FBLIM1; FBLP-1; FBLP1
UniProt ID: (Human) Q8WUP2
Entrez Gene ID: (Human) 54751