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Abnova
FBXL21 Monoclonal Antibody (4A1)
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产品信息
H00026223-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4A1
抗原
FBXL21 (NP_036291, 167 a.a. approximately 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: VSKVVLGRVG LNCPRLIELV VCANDLQPLD NELICIAEHC TNLTALGLSK CEVSCSAFIR FVRLCERRLT QLSVMEEVLI PDEDYSLDEI HTEVSKYLGR VWFPDVMPLW
靶标信息
FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-box and leucine-rich repeat protein 21; F-box and leucine-rich repeat protein 3 pseudogene; F-box and leucine-rich repeat protein 3B; F-box protein Fbl3b; F-box/LRR-repeat protein 3B
基因别名: Fbl21; FBL3B; FBXL3B; FBXL3P
Entrez Gene ID: (Human) 26223
