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Invitrogen
FBXO33 Polyclonal Antibody
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产品信息
PA5-61275
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: NNRNLQKFSL FGDISVLQQQ GSLSNTYLSK VDPDGKKIKQ IQQLFEEILS NSRQLKWLSC GFMLEIVTPT SLSSLSNAVA NTMEHLSLLD NNIPGNSTLI TAVELERFVN LHSLALDFCD FTAEMARVL
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
靶标信息
FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-box only protein 33
基因别名: BMND12; c14_5247; FBX33; FBXO33
UniProt ID: (Human) Q7Z6M2
Entrez Gene ID: (Human) 254170
