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Abnova
FBXO5 Monoclonal Antibody (5H7)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00026271-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
5H7
抗原
FBXO5 (NP_036309, 358 a.a. approximately 446 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: RHNEFSEVAK TLKKNESLKA CIRCNSPAKY DCYLQRATCK REGCGFDYCT KCLCNYHTTK DCSDGKLLKA SCKIGPLPGT KKSKKNLRR
靶标信息
F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: early fission inhibitory protein 1; early mitotic inhibitor 1; F-box protein Fbx5; unnamed protein product
基因别名: EMI1; FBX5; Fbxo31
UniProt ID: (Human) Q9UKT4
Entrez Gene ID: (Human) 26271
regulation of DNA replication
cellular response to DNA damage stimulus
regulation of mitotic nuclear division
regulation of mitotic cell cycle
positive regulation of cell proliferation
negative regulation of cell cycle process
positive regulation of G2/M transition of mitotic cell cycle
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
negative regulation of DNA endoreduplication
positive regulation of osteoblast differentiation
negative regulation of meiotic nuclear division
negative regulation of mitotic metaphase/anaphase transition
negative regulation of ubiquitin-protein transferase activity
positive regulation of biomineral tissue development
negative regulation of ubiquitin protein ligase activity
positive regulation of mesenchymal stem cell migration
negative regulation of cellular senescence
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
