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Sequence of this protein is as follows: MDAPHSKAAL DSINELPENI LLELFTHVPA RQLLLNCRLV CSLWRDLIDL MTLWKRKCLR EGFITKDWDQ PVADWKIFYF LRSLHRNLLR NPCAEEDMFA WQIDFNGGDR WKVESLPGAH GTDFPDPKVK KYFVTSYEMC LKSQLVDLVA EGYWEELLDT FRPDIVVKDW FAARADCGCT YQLKVQLASA DYFVLASFEP PPVTIQQWNN ATWTEVSYTF SDYPRGVRYI LFQHGGRDTQ YWAGWYGPRV TNSSIVVSPK MTRNQASSEA QPGQKHGQEE AAQSPYRAVV QIF
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: F-box only protein 6; F-box protein FBG2; F-box protein Fbx6; F-box protein that recognizes sugar chains 2; F-box/G-domain protein 2; FBG1; Fbs1; FBX2; NFB42; RP3-330O12.3
基因别名: FBG2; FBS2; FBX6; Fbx6b; FBXO6
UniProt ID: (Human) Q9NRD1
Entrez Gene ID: (Human) 26270