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Invitrogen
FBXW10 Polyclonal Antibody
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产品信息
PA5-43814
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human FBXW10 (aa 180-229).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: SPEKDHSSKS ATSQVYWTAK TQHTSLPLSK APENEHLLGA ASNPEEPWRN
Sequence homology: Human: 100%
靶标信息
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-box and WD-40 domain protein 10; F-box and WD-40 domain-containing protein 10; F-box/WD repeat-containing protein 10; testicular tissue protein Li 69; ubiquitin ligase specificity factor; Ubiquitin ligase-specificity factor
基因别名: Fbw10; FBXW10; HREP; SM25H2; SM2SH2
UniProt ID: (Human) Q5XX13
Entrez Gene ID: (Human) 10517
