Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Abnova
FBXW11 Monoclonal Antibody (2E7)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
H00023291-M03
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2E7
抗原
FBXW11 (AAH26213, 1 a.a. approximately 529 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MEPDSVIEDK TIELMNTSVM EDQNEDESPK KNTLWQISNG TSSVIVSRKR PSEGNYQKEK DLCIKYFDQW SESDQVEFVE HLISRMCHYQ HGHINSYLKP MLQRDFITAL PEQGLDHIAE NILSYLDARS LCAAELVCKE WQRVISEGML WKKLIERMVR TDPLWKGLSE RRGWDQYLFK NRPTDGPPNS FYRSLYPKII QDIETIESNW RCGRHNLQRI QCRSENSKGV YCLQYDDEKI ISGLRDNSIK IWDKTSLECL KVLTGHTGSV LCLQYDERVI VTGSSDSTVR VWDVNTGEVL NTLIHHNEAV LHLRFSNGLM VTCSKDRSIA VWDMASATDI TLRRVLVGHR AAVNVVDFDD KYIVSASGDR TIKVWSTSTC EFVRTLNGHK RGIACLQYRD RLVVSGSSDN TIRLWDIECG ACLRVLEGHE ELVRCIRFDN KRIVSGAYDG KIKVWDLQAA LDPRAPASTL CLRTLVEHSG RVFRLQFDEF QIISSSHDDT ILIWDFLNVP PSAQNETRSP SRTYTYISR
靶标信息
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: beta-transducin repeat-containing protein 2; F-box and WD repeats protein beta-TrCP2; F-box and WD-40 domain protein 11; F-box and WD-40 domain protein 1B; F-box protein Fbw1b; F-box/WD repeat-containing protein 11; F-box/WD repeat-containing protein 1B; Homologous to Slimb protein; HOS
基因别名: BTRC2; BTRCP2; Fbw11; FBW1B; FBXW11; FBXW1B; Hos; KIAA0696
UniProt ID: (Human) Q9UKB1
Entrez Gene ID: (Human) 23291
G2/M transition of mitotic cell cycle
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
protein dephosphorylation
Wnt signaling pathway
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein destabilization
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
negative regulation of NF-kappaB import into nucleus
positive regulation of circadian rhythm
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
T cell receptor signaling pathway
stress-activated MAPK cascade
