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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PQVFLTESLL RPSEGSVPLS TFLPHKLCAS ACWTPKVKNR ITLMSQSSTG KKTEFITFDL TTKKTGGQTV IQAYEIASFQ VAAHLKCPIW MGA
Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 43%.
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: F-box and WD-40 domain-containing protein 12; F-box only protein 35; F-box/WD repeat-containing protein 12
基因别名: FBW12; FBXO12; FBXO35; FBXW12
Entrez Gene ID: (Human) 285231