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FCER1G Antibody (PA5-115222) in ICC/IF
Immunocytochemistry analysis of FCER1G in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115222) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115222
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FCER1G(Accession P30273), corresponding to amino acid residues K52-Q86.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total FCER1G.
靶标信息
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fc fragment of IgE receptor Ig; Fc fragment of IgE, high affinity I, receptor for; Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; Fc receptor gamma-chain; Fc receptor, IgE, high affinity I, gamma polypeptide; fc-epsilon RI-gamma; Fc-epsilon-receptor gamma-chain protein precursor; FcepsilonRI gamma chain; FcepsilonRIgamma; fceRI gamma; fcRgamma; gamma polypeptide; high affinity IgE receptor gamma subunit precursor; igE Fc receptor subunit gamma; immunoglobulin E receptor, high affinity, gamma chain; unnamed protein product
基因别名: CD23; Fce1g; FcepsilonRI; FcR-gamma; FcR[g]; FCRG; FcRgamma; Ly-50
UniProt ID: (Human) P30273, (Rat) P20411, (Mouse) P20491
Entrez Gene ID: (Human) 2207, (Rat) 25441, (Mouse) 14127
positive regulation of type IIa hypersensitivity
positive regulation of type III hypersensitivity
positive regulation of type I hypersensitivity
neutrophil activation involved in immune response
T cell differentiation involved in immune response
Fc receptor mediated stimulatory signaling pathway
serotonin secretion by platelet
phagocytosis, engulfment
signal transduction
cell surface receptor signaling pathway
integrin-mediated signaling pathway
regulation of platelet activation
immunoglobulin mediated immune response
antigen processing and presentation of exogenous peptide antigen via MHC class II
osteoclast differentiation
neutrophil chemotaxis
receptor internalization
regulation of tumor necrosis factor production
positive regulation of interleukin-10 production
positive regulation of interleukin-2 production
positive regulation of interleukin-4 production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of mast cell cytokine production
negative regulation of mast cell apoptotic process
Fc-gamma receptor signaling pathway
Fc-epsilon receptor signaling pathway
interleukin-3-mediated signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I
defense response to bacterium
positive regulation of mast cell degranulation
innate immune response
mast cell activation
positive regulation of phagocytosis
regulation of immune response
positive regulation of immune response
positive regulation of T cell receptor signaling pathway
cellular response to low-density lipoprotein particle stimulus
protein localization to plasma membrane
Fc receptor-mediated immune complex endocytosis
positive regulation of protein localization to cell surface
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