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Invitrogen
FCGR2A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116569
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 34-316 of human FCGR2A (NP_0011296911)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.26 mg/mL
规格
226 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: K-562, Mouse spleen
Immunogen sequence: QAAAPPKAVL KLEPPWINVL QEDSVTLTCQ GARSPESDSI QWFHNGNLIP THTQPSYRFK ANNNDSGEYT CQTGQTSLSD PVHLTVLSEW LVLQTPHLEF QEGETIMLRC HSWKDKPLVK VTFFQNGKSQ KFSHLDPTFS IPQANHSHSG DYHCTGNIGY TLFSSKPVTI TVQVPSMGSS SPMGIIVAVV IATAVAAIVA AVVALIYCRK KRISANSTDP VKAAQFEPPG RQMIAIRKRQ LEETNNDYET ADGGYMTLNP RAPTDDDKNI YLTLPPNDHV NSNN
靶标信息
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fc fragment of IgG low affinity IIa receptor for (CD32); Fc fragment of IgG receptor IIa; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc gamma receptor IIa; Fc gamma receptor RIIa3; Fc receptor, IgG, low affinity III; fc-gamma-RIIa; FcgRIIa3 splice variant; fcRII-a; IgG Fc fragment receptor precursor; IgG Fc receptor alpha-Fc-gamma-RII; igG Fc receptor II-a; igG Fc receptor III; IgG Fc receptor precursor; Immunoglobulin G Fc receptor II; unnamed protein product
基因别名: CD32; CD32A; CDw32; fc-gamma RIII; FCG2; FcgammaRIIa; FcGR; FCGR2; FCGR2A1; Fcgr3; Fcgr3a; fcRIII; IGFR2
UniProt ID: (Human) P12318, (Rat) P27645
Entrez Gene ID: (Human) 2212, (Rat) 116591
antibody-dependent cellular cytotoxicity
positive regulation of type IIa hypersensitivity
positive regulation of type III hypersensitivity
positive regulation of type I hypersensitivity
regulation of antibody-dependent cellular cytotoxicity
serotonin secretion
regulation of immune system process
phagocytosis, recognition
phagocytosis, engulfment
cell surface receptor signaling pathway
nerve development
neutrophil chemotaxis
regulation of tumor necrosis factor production
positive regulation of tumor necrosis factor production
Fc-gamma receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I
mast cell activation
regulation of phagocytosis
positive regulation of phagocytosis
regulation of immune response
regulation of Fc receptor mediated stimulatory signaling pathway
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