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Abnova
FCRL1 Polyclonal Antibody, MaxPab™
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产品信息
H00115350-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FCRL1 (NP_443170.1, 1 a.a. approximately 429 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLPRLLLLIC APLCEPAELF LIASPSHPTE GSPVTLTCKM PFLQSSDAQF QFCFFRDTRA LGPGWSSSPK LQIAAMWKED TGSYWCEAQT MASKVLRSRR SQINVHRVPV ADVSLETQPP GGQVMEGDRL VLICSVAMGT GDITFLWYKG AVGLNLQSKT QRSLTAEYEI PSVRESDAEQ YYCVAENGYG PSPSGLVSIT VRIPVSRPIL MLRAPRAQAA VEDVLELHCE ALRGSPPILY WFYHEDITLG SRSAPSGGGA SFNLSLTEEH SGNYSCEANN GLGAQRSEAV TLNFTVPTGA RSNHLTSGVI EGLLSTLGPA TVALLFCYGL KRKIGRRSAR DPLRSLPSPL PQEFTYLNSP TPGQLQPIYE NVNVVSGDEV YSLAYYNQPE QESVAAETLG THMEDKVSLD IYSRLRKANI TDVDYEDAM
靶标信息
Fc receptor-like 1 (FCRL1) is a gene situated on chromosome 1q23, encoding a protein that is part of the Fc receptor-like family, which shares structural similarities with classical Fc receptors involved in immune responses. FCRL1 is predominantly expressed in B lymphocytes and is thought to play a role in the regulation of immune functions, particularly those associated with B cell development and differentiation. Although its precise biological function is not fully understood, it is believed to act as an immunomodulatory receptor that could influence B cell signaling pathways. The expression patterns of FCRL1 suggest possible involvement in autoimmune disorders and immune system modulation, potentially contributing to pathological conditions when dysregulated. Research into FCRL1 and other Fc receptor-like proteins continues to explore their contributions to immune homeostasis and potential as therapeutic targets in diseases involving B cell dysfunction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD307a; CD307a antigen; Fc receptor homolog 1; Fc receptor-like 1; Fc receptor-like protein 1; FcR-like protein 1; FcRH1; FCRH1DKFZp667O1421; hIFGP1; IFGP family protein 1; Immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42
基因别名: CD307a; FCRH1; FCRL1; IFGP1; IRTA5
UniProt ID: (Human) Q96LA6
Entrez Gene ID: (Human) 115350
