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Invitrogen
FCRL1 Monoclonal Antibody (282415)
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产品信息
MA5-23984
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
282415
抗原
Mouse myeloma cell line NS0-derived recombinant human FCRL1/FcRH1 Ala17-His304
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In Western blots, no cross-reactivity with recombinant human (rh) FCRL2, 3, 4, or 5 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Fc receptor-like 1 (FCRL1) is a gene situated on chromosome 1q23, encoding a protein that is part of the Fc receptor-like family, which shares structural similarities with classical Fc receptors involved in immune responses. FCRL1 is predominantly expressed in B lymphocytes and is thought to play a role in the regulation of immune functions, particularly those associated with B cell development and differentiation. Although its precise biological function is not fully understood, it is believed to act as an immunomodulatory receptor that could influence B cell signaling pathways. The expression patterns of FCRL1 suggest possible involvement in autoimmune disorders and immune system modulation, potentially contributing to pathological conditions when dysregulated. Research into FCRL1 and other Fc receptor-like proteins continues to explore their contributions to immune homeostasis and potential as therapeutic targets in diseases involving B cell dysfunction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD307a; CD307a antigen; Fc receptor homolog 1; Fc receptor-like 1; Fc receptor-like protein 1; FcR-like protein 1; FcRH1; FCRH1DKFZp667O1421; hIFGP1; IFGP family protein 1; Immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42
基因别名: CD307a; FCRH1; FCRL1; IFGP1; IRTA5
UniProt ID: (Human) Q96LA6
Entrez Gene ID: (Human) 115350
