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Abnova
FCRLA Polyclonal Antibody, MaxPab™
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产品信息
H00084824-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FCRLA (NP_116127.3, 1 a.a. approximately 376 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLKKISVGVA GDLNTVTMKL GCVLMAWALY LSLGVLWVAQ MLLAASFETL QCEGPVCTEE SSCHTEDDLT DAREAGFQVK AYTFSEPFHL IVSYDWLILQ GPAKPVFEGD LLVLRCQAWQ DWPLTQVTFY RDGSALGPPG PNREFSITVV QKADSGHYHC SGIFQSPGPG IPETASVVAI TVQELFPAPI LRAVPSAEPQ AGSPMTLSCQ TKLPLQRSAA RLLFSFYKDG RIVQSRGLSS EFQIPTASED HSGSYWCEAA TEDNQVWKQS PQLEIRVQGA SSSAAPPTLN PAPQKSAAPG TAPEEAPGPL PPPPTPSSED PGFSSPLGMP DPHLYHQMGL LLKHMQDVRV LLGHLLMELR ELSGHRKPGT TKATAE
靶标信息
Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fc receptor homolog expressed in B cells (FREB); Fc receptor homolog expressed in B-cells; Fc receptor related protein X; Fc receptor-like A; Fc receptor-like and mucin-like 1; Fc receptor-like and mucin-like protein 1; Fc receptor-like protein; Fc receptor-related protein X; FcRX
基因别名: FCRL; FCRL1; FCRLA; FCRLb; FCRLc1; FCRLc2; FCRLd; FCRLe; FCRLM1; FCRLX; FCRX; FREB; UNQ291/PRO329
UniProt ID: (Human) Q7L513
Entrez Gene ID: (Human) 84824
