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Abnova
FES Monoclonal Antibody (3A3-1E5)
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产品信息
H00002242-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3A3-1E5
抗原
FES (AAH35357, 1 a.a. approximately 822 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MGFSSELCSP QGHGVLQQMQ EAELRLLEGM RKWMAQRVKS DREYAGLLHH MSLQDSGGQS RAISPDSPIS QSWAEITSQT EGLSRLLRQH AEDLNSGPLS KLSLLIRERQ QLRKTYSEQW QQLQQELTKT HSQDIEKLKS QYRALARDSA QAKRKYQEAS KDKDRDKAKD KYVRSLWKLF AHHNRYVLGV RAAQLHHQHH HQLLLPGLLR SLQDLHEEMA CILKEILQEY LEISSLVQDE VVAIHREMAA AAARIQPEAE YQGFLRQYGS APDVPPCVTF DESLLEEGEP LEPGELQLNE LTVESVQHTL TSVTDELAVA TEMVFRRQEM VTQLQQELRN EEENTHPRER VQLLGKRQVL QEALQGLQVA LCSQAKLQAQ QELLQTKLEH LGPGEPPPVL LLQDDRHSTS SSEQEREGGR TPTLEILKSH ISGIFRPKFS LPPPLQLIPE VQKPLHEQLW YHGAIPRAEV AELLVHSGDF LVRESQGKQE YVLSVLWDGL PRHFIIQSLD NLYRLEGEGF PSIPLLIDHL LSTQQPLTKK SGVVLHRAVP KDKWVLNHED LVLGEQIGRG NFGEVFSGRL RADNTLVAVK SCRETLPPDL KAKFLQEARI LKQYSHPNIV RLIGVCTQKQ PIYIVMELVQ GGDFLTFLRT EGARLRVKTL LQMVGDAAAG MEYLESKCCI HRDLAARNCL VTEKNVLKIS DFGMSREEAD GVYAASGGLR QVPVKWTAPE ALNYGRYSSE SDVWSFGILL WETFSLGASP YPNLSNQQTR EFVEKGGRLP CPELCPDAVF RLMEQCWAYE PGQRPSFSTI YQELQSIRKR HR
靶标信息
FES (FPS) is a tyrosine protein kinase that is required for maintenance of cellular transformation. Its chromosomal location is linked to a specific translocation event identified in patients with acute promyelocytic leukemia, and it is also involved in normal hematopoiesis. Alternative splicing results in multiple variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 2.7.10.2; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog; feline sarcoma oncogene; Feline sarcoma/Fujinami avian sarcoma oncogene homolog; Oncogene FES, feline sarcoma virus; p93c-fes; Proto-oncogene c-Fes; Proto-oncogene c-Fps; proto-oncogene tyrosine-protein kinase Fes/Fps; Tyrosine-protein kinase Fes/Fps; Variant 4
基因别名: FES; FPS
UniProt ID: (Human) P07332
Entrez Gene ID: (Human) 2242
microtubule bundle formation
protein phosphorylation
chemotaxis
epidermal growth factor receptor signaling pathway
multicellular organism development
cell proliferation
regulation of cell shape
positive regulation of neuron projection development
peptidyl-tyrosine phosphorylation
regulation of cell adhesion
positive regulation of microtubule polymerization
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
regulation of mast cell degranulation
innate immune response
regulation of cell differentiation
positive regulation of myeloid cell differentiation
protein autophosphorylation
centrosome organization
regulation of vesicle-mediated transport
regulation of cell motility
positive regulation of actin cytoskeleton reorganization
