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Invitrogen
FEZ1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5150649
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Highest antigen sequence identity to the following orthologs: Mouse- 98%, Rat- 96%.
Sequence of this protein is as follows: EEEVLEEEDG GETSSQADSV LLQEMQALTQ TFNNNWSYEG LRHMSGSELT E
靶标信息
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F37; FEZ1; unnamed protein product; zygin 1; zygin I; zygin-1
基因别名: UNC-76
UniProt ID: (Human) Q99689
Entrez Gene ID: (Human) 9638
mitochondrion organization
cell adhesion
nervous system development
axon guidance
positive regulation of neuron projection development
hippocampus development
establishment of cell polarity
establishment of mitochondrion localization
positive regulation of anterograde axonal transport of mitochondrion
cellular response to growth factor stimulus
negative regulation of autophagosome assembly
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