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Invitrogen
FEZ2 Polyclonal Antibody
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产品信息
PA5-20459
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide from near the center of human FEZ2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is NIH-3T3 cell lysate.
PA5-20459 can be used with blocking peptide PEP-0576.
靶标信息
Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fasciculation and elongation protein zeta 2 (zygin II); Fasciculation and elongation protein zeta-2; pre-T/NK cell associated protein (3Cl); synaptotagmin interacting protein zyginII; zygin 2; Zygin II; Zygin-2; Zygin-related protein types I/II
基因别名: 9030616F16; D17Ertd315e; FEZ2; HUM3CL; Zrp
UniProt ID: (Human) Q9UHY8, (Mouse) Q6TYB5, (Rat) P97578
Entrez Gene ID: (Human) 9637, (Mouse) 225020, (Rat) 94269
