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Invitrogen
FGD5 Polyclonal Antibody
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产品信息
PA5-53187
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: NSPQLKSRTG KLRASESPSS LIFYRDGKRK GVPFSRTVSR VESFEDRSRP PFLPLPLTKP RSISFPSADT SDYENIPAMN SDYENIQIPP RRPARAGAFT KLFEDQSRAL STANENDGYV D
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.
靶标信息
FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation. It may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation and may play a role in regulating the actin cytoskeleton and cell shape.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FYVE, RhoGEF and PH domain-containing protein 5; Zinc finger FYVE domain-containing protein 23
基因别名: FGD5; ZFYVE23
UniProt ID: (Human) Q6ZNL6
Entrez Gene ID: (Human) 152273
