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Invitrogen
FGF1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-50489
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region derived from internal residues of human Fibroblast growth factor 1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.2 mg/mL
规格
120 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total FGF1 protein.
靶标信息
FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acidic fibroblast growth factor; aFGF; beta-endothelial cell growth factor; ECGF; Endothelial cell growth factor; endothelial cell growth factor, alpha; endothelial cell growth factor, beta; FGF; FGF-1; Fibroblast growth factor; Fibroblast growth factor 1; fibroblast growth factor 1 (acidic); Fibroblast growth factor 1 (heparin binding); H-FGF-a; HBGF-1; Heparin-binding growth factor 1; M-FGF-a; unnamed protein product
基因别名: AFGF; Dffrx; ECGF; ECGF-beta; ECGFA; ECGFB; Fam; FGF-1; FGF-alpha; FGF1; FGFA; GLIO703; HBGF-1; HBGF1
UniProt ID: (Human) P05230, (Rat) P61149, (Mouse) P61148
Entrez Gene ID: (Human) 2246, (Rat) 25317, (Mouse) 14164
angiogenesis
branching involved in ureteric bud morphogenesis
organ induction
signal transduction
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
anatomical structure morphogenesis
positive regulation of endothelial cell migration
neurogenesis
cell differentiation
lung development
regulation of cell migration
positive regulation of cell migration
activation of protein kinase B activity
cellular response to heat
wound healing
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of cholesterol biosynthetic process
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
epithelial cell proliferation
positive regulation of epithelial cell proliferation
positive regulation of cell division
branch elongation involved in ureteric bud branching
positive regulation of ERK1 and ERK2 cascade
mesonephric epithelium development
regulation of endothelial tube morphogenesis
positive regulation of intracellular signal transduction
positive regulation of sprouting angiogenesis
regulation of morphogenesis of an epithelium
regulation of endothelial cell chemotaxis to fibroblast growth factor
positive regulation of protein phosphorylation
cell proliferation
multicellular organism development
positive regulation of transcription, DNA-templated
cardiac muscle cell proliferation
vasculogenesis involved in coronary vascular morphogenesis
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