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Invitrogen
FGF9 Polyclonal Antibody
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FIGURE: 1 / 2
FGF9 Antibody (PA5-92930) in WB
Western blot analysis of FGF9 in extracts of various cell lines. Samples were incubated with FGF9 Polyclonal antibody (Product # PA5-92930) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
PA5-92930
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGF9 (NP_0020011)
Conjugate
Form
Liquid
Concentration
2.2 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Mouse kidney
Immunogen sequence: MAPLGEVGNY FGVQDAVPFG NVPVLPVDSP VLLSDHLGQS EAGGLPRGPA VTDLDHLKGI LRRRQLYCRT GFHLEIFPNG TIQGTRKDHS RFGILEFISI
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: elbow knee synostosis; FGF; FGF-9; Fibroblast growth factor; Fibroblast growth factor 9; fibroblast growth factor 9 (glia-activating factor); GAF; glia activating factor; Glia-activating factor; HBGF-9; Heparin-binding growth factor 9; M-FGF-9
Gene Aliases: Eks; FGF-9; FGF9; GAF; HBFG-9; HBGF-9; SYNS3
UniProt ID: (Human) P31371, (Rat) P36364, (Mouse) P54130
Entrez Gene ID: (Human) 2254, (Rat) 25444, (Mouse) 14180
protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
fibroblast growth factor receptor binding
growth factor activity
heparin binding
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
receptor binding
growth factor
intercellular signal molecule
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
angiogenesis
osteoblast differentiation
eye development
positive regulation of mesenchymal cell proliferation
chondrocyte differentiation
protein import into nucleus
signal transduction
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
male gonad development
positive regulation of gene expression
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
substantia nigra development
negative regulation of Wnt signaling pathway
male sex determination
embryonic limb morphogenesis
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of activin receptor signaling pathway
phosphatidylinositol-3-phosphate biosynthetic process
inner ear morphogenesis
positive regulation of MAPK cascade
positive regulation of GTPase activity
positive regulation of smoothened signaling pathway
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
regulation of timing of cell differentiation
embryonic digestive tract development
embryonic skeletal system development
positive regulation of epithelial cell proliferation
positive regulation of cell division
positive regulation of cardiac muscle cell proliferation
lung-associated mesenchyme development
positive regulation of canonical Wnt signaling pathway
lung development
cardiac left ventricle morphogenesis
cardiac ventricle development
multicellular organism development
cell differentiation
positive regulation of transcription, DNA-templated
vasculogenesis involved in coronary vascular morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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