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Invitrogen
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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human FGFBP3.
FGFBP3 is a heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FGF-binding protein 3; FGF-BP3; FGFBP-3; Fibroblast growth factor-binding protein 3
基因别名: C10orf13; FGF-BP3; FGFBP3; PSEC0101
UniProt ID: (Human) Q8TAT2
Entrez Gene ID: (Human) 143282