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Invitrogen
FHL1 Polyclonal Antibody
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图: 1 / 3
FHL1 Antibody (PA5-115231) in ICC/IF
Immunocytochemistry analysis of FHL1 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115231) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115231
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FHL1(Accession Q13642), corresponding to amino acid residues L255-T275.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total FHL1.
靶标信息
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bA535K18.1; FHL-1; FHL1; FHL1B; formerly SLIM1; Four and a half LIM domains protein 1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; heart protein with four and a half LIM domains; KYO-T; KyoT; LIM protein SLIMMER; MGC111107; RAM14-1; RBP-associated molecule 14-1; RP11-535K18.1; skeletal and cardiac muscle SLIM isoform; Skeletal muscle LIM-protein 1; SLIM; unnamed protein product
基因别名: FCMSU; FHL-1; FHL1; FHL1A; FHL1B; FLH1A; KYOT; RAM14-1; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA
UniProt ID: (Human) Q13642, (Rat) Q9WUH4, (Mouse) P97447
Entrez Gene ID: (Human) 2273, (Rat) 25177, (Mouse) 14199
muscle organ development
organ morphogenesis
negative regulation of G2/M transition of mitotic cell cycle
cell differentiation
negative regulation of cell growth
regulation of atrial cardiac muscle cell membrane depolarization
positive regulation of potassium ion transmembrane transport
negative regulation of G1/S transition of mitotic cell cycle
regulation of membrane depolarization
multicellular organism development
positive regulation of potassium ion transport
regulation of potassium ion transmembrane transporter activity
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