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Invitrogen
FHL1 Recombinant Rabbit Monoclonal Antibody (K01_2M41)
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FHL1 Antibody (MA564064) in IHC (P)
Immunohistochemistry (Paraffin) analysis of FHL1 in paraffin-embedded Human breast cancer tissue. Samples were incubated with FHL1 recombinant monoclonal (Product # MA564064). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
产品信息
MA564064
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_2M41
抗原
Recombinant protein of human FHL1 (aa 2-323).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
50mM tris glycine, pH 7.4, with 0.05% BSA, 150mM NaCl, 40% glycerol
内含物
0.01% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AEKFDCHYCR DPLQGKKYVQ KDGHHCCLKC FDKFCANTCV ECRKPIGADS KEVHYKNRFW HDTCFRCAKC LHPLANETFV AKDNKILCNK CTTREDSPKC KGCFKAIVAG DQNVEYKGTV WHKDCFTCSN CKQVIGTGSF FPKGEDFYCV TCHETKFAKH CVKCNKAITS GGITYQDQPW HADCFVCVTC SKKLAGQRFT AVEDQYYCVD CYKNFVAKKC AGCKNPITGK RTVSRVSHPV SKARKPPVCH GKRLPLTLFP SANLRGRHPG GERTCPSWVV VLYRKNRSLA APRGPGLVKA PVWWPMKDNP GTTTASTAKN AP
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%, Pig - 98%, Cynomolgus monkey - 100%.
靶标信息
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bA535K18.1; FHL-1; Four and a half LIM domains protein 1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYO-T; LIM protein SLIMMER; MGC111107; RP11-535K18.1; Skeletal muscle LIM-protein 1; SLIM
基因别名: FHL-1; FHL1; FHL1A; FHL1B; FLH1A; KYOT; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA
UniProt ID: (Human) Q13642
Entrez Gene ID: (Human) 2273
regulation of membrane depolarization
muscle organ development
organ morphogenesis
negative regulation of G2/M transition of mitotic cell cycle
cell differentiation
negative regulation of cell growth
positive regulation of potassium ion transport
regulation of potassium ion transmembrane transporter activity
negative regulation of G1/S transition of mitotic cell cycle
