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Invitrogen
FHL2 Polyclonal Antibody
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FHL2 Antibody (PA5-29906) in IHC (P)
FHL2 Polyclonal Antibody detects FHL2 protein at cytosol and nucleus on mouse heart by immunohistochemical analysis. Sample: Paraffin-embedded mouse heart. FHL2 Polyclonal Antibody (Product # PA5-29906) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-29906
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human FHL2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.79 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLa, mouse brain.
Predicted reactivity: Mouse (93%), Rat (92%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aging-associated gene 11; down-regulated in rhabdomyosarcoma LIM protein; FHL-2; Four and a half LIM domains protein 2; LIM domain protein DRAL; OTTHUMP00000203164; OTTHUMP00000203168; OTTHUMP00000203169; Skeletal muscle LIM-protein 3; SLIM-3
基因别名: AAG11; DRAL; FHL-2; FHL2; SLIM-3; SLIM3
UniProt ID: (Human) Q14192, (Mouse) O70433
Entrez Gene ID: (Human) 2274, (Mouse) 14200
negative regulation of transcription from RNA polymerase II promoter
osteoblast differentiation
transcription, DNA-templated
response to hormone
androgen receptor signaling pathway
negative regulation of apoptotic process
positive regulation of transcription, DNA-templated
atrial cardiac muscle cell development
ventricular cardiac muscle cell development
heart trabecula formation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
