Invitrogen

FIBB Monoclonal Antibody (6D12)

Name: FIBB Monoclonal Antibody (6D12)
Brand: Invitrogen
SKU: MA5-49187

查看其他16个FIBB抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

FIBB Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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FIBB Antibody (MA5-49187) in IHC (P)

Immunohistochemistry analysis of FIBB in paraffin-embedded section of human liver cancer tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with FIBB Monoclonal antibody (Product # MA5-49187) using a dilution of 2 μg/mL overnight at 4°C. Biotinylated goat anti-mouse IgG was used... View More

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Immunogen image

Immunogen Image FIBB Monoclonal Antibody (6D12)

产品信息

MA5-49187

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.25-0.5 µg/mL

免疫组化（石蜡） (IHC (P))

2-5 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

6D12

抗原

A synthetic peptide corresponding to a sequence in the middle region of human FGB (193-225aa TNLRVLRSILENLRSKIQKLESDVSAQMEYCRT).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

500 µg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 4mg trehalose

内含物

no preservative

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_3074845

产品详细信息

Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Immunogen sequence is different from the related mouse sequence by three amino acids, and from the related rat sequence by five amino acids.

Positive Control - WB: human HEPG2 whole cell. IHC: human liver cancer tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

靶标信息

FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

仅用于科研。不用于诊断过程。未经明确授权不得转售。