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Abnova
FIGLA Monoclonal Antibody (6A10)
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产品信息
H00344018-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
6A10
抗原
FIGLA (NP_001004311.1, 110 a.a. approximately 219 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: ATEYIQVLSD LLEGAKDSKK QDPDEQSYSN NTSESHTSSA RQLSRNITQH ISCAFGLKNE EEGPWADGGS GEPAHACRHS VMSTTEIISP TRSLDRFPEV ELLSHRLPQV
靶标信息
Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHc8; Class C basic helix-loop-helix protein 8; Factor in the germline alpha; FIGalpha; folliculogenesis specific basic helix-loop-helix; Folliculogenesis-specific basic helix-loop-helix protein; Transcription factor FIGa
基因别名: BHLHC8; FIGALPHA; FIGLA; POF6
UniProt ID: (Human) Q6QHK4
Entrez Gene ID: (Human) 344018
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor binding
sequence-specific DNA binding
protein dimerization activity
basic helix-loop-helix transcription factor
