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Invitrogen
FIP1L1 Polyclonal Antibody
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产品信息
PA5-84366
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DVHVTIGDIK TGAPQYGSYG TAPVNLNIKT GGRVYGTTGT KVKGVDLDAP GSINGVPLLE VDLDSFEDKP WRKPGADLSD YFNYGFNEDT WK
Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 98%.
靶标信息
FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp586K0717; Factor interacting with PAP; FIP1 like 1; FIP1-like 1 protein; FIP1L1 cleavage and polyadenylation specific factor subunit; FLJ33619; hFip1; Pre-mRNA 3'-end-processing factor FIP1; Rearranged in hypereosinophilia
基因别名: FIP1; FIP1L1; hFip1; RHE
UniProt ID: (Human) Q6UN15
Entrez Gene ID: (Human) 81608
