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Proteintech
CD357 (GITR) Monoclonal Antibody (DTA-1), FITC
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CD357 (GITR) Antibody (FITC-65102100UG) in Flow
1X10^6 Mouse splenocytes were surface stained with 0.125 µg PE-Anti-Mouse CD4 (PE-65104, clone GK1.5), 0.125 µg APC-Anti-Mouse CD25 (APC-65137, clone PC61.5) and 0.06 µg FITC-Anti-Mouse CD357 (GITR) (Product # FITC-65102100UG), clone DTA-1). Cells were not fixed. CD4+ lymphocytes were gated for analysis ofCD25 and CD357 (GITR) staining.
产品信息
FITC-65102100UG
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
DTA-1
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 0.1% gelatin
内含物
0.09% sodium azide
保存条件
4°C, store in dark
运输条件
Wet ice
靶标信息
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD357; Glucocorticoid-induced TNFR-related protein; PRO364; Tumor necrosis factor receptor superfamily member 18; UNQ319
基因别名: AITR; Gitr; Tnfrsf18
UniProt ID: (Mouse) O35714
Entrez Gene ID: (Mouse) 21936
