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Invitrogen
FK506 Monoclonal Antibody (4C12)
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产品信息
MA5-49653
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
4C12
抗原
Conjugate of TRL hapten and KLH
偶联物
形式
Liquid
浓度
4.2 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody tested in indirect ELISA
靶标信息
Tacrolimus is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent. [National Center for Biotechnology Information. PubChem Compound Database; CID=445643].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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