Search
Bethyl Laboratories
FKBP4/FKBP52 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 2
FKBP4/FKBP52 Antibody (A301-428A) in WB
Detection of human and mouse FKBP4/FKBP52 by western blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg), HEK293T (T; 50 µg) and mouse NIH 3T3 (M; 50 µg) cells. Antibodies: Affinity purified rabbit anti-FKBP4/FKBP52 antibody (Product # A301-428A) (lot A301-428A-1) used for WB at 0.04 µg/mL. Detection: Chemiluminescence with exposure time of 10 seconds.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
A301-428A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 440 and 459 human FK506 binding protein 4.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.20 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rabbit
靶标信息
FKBP4, encoding FK506-binding protein 4, is part of the immunophilin family and plays roles in cellular processes like protein folding and trafficking. The FKBP4 gene is located on chromosome 12, where it encodes a protein involved in modulating the androgen receptor signaling pathway and has been implicated in various cancers, including non-small-cell lung cancer (NSCLC) and hepatocellular carcinoma (HCC). Structural variants of FKBP4 found through exome sequencing have shown potential deleterious effects on protein function. This gene is associated with cell proliferation, apoptosis, migration, and invasion in cancer cells. FKBP4 also influences metabolic processes, such as glycolysis, thereby contributing to cancer cell survival and growth. Importantly, FKBP4 has a role in disorders of sexual development due to its regulatory interaction with hormone signaling pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 51 kDa FK506-binding protein; 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; FK506-binding protein 4; FKBP-4; FKBP51; FKBP59; HBI; HSP-binding immunophilin; Immunophilin FKBP52; p59; Peptidyl-prolyl cis-trans isomerase FKBP4; PPIase FKBP4; Rotamase
基因别名: 59kDa; AL022792; AW208983; FKBP-4; FKBP-52; FKBP4; FKBP52; FKPB52; p59
UniProt ID: (Mouse) P30416
Entrez Gene ID: (Mouse) 14228
protein peptidyl-prolyl isomerization
protein folding
steroid hormone receptor complex assembly
copper ion transport
embryo implantation
androgen receptor signaling pathway
prostate gland development
negative regulation of microtubule polymerization
protein complex localization
male sex differentiation
reproductive structure development
chaperone-mediated protein folding
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
