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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Samples: A-549, THP-1, U-937
Immunogen sequence: DAYPTFLAVL WSAGLLCSQV PAAFAGLMYL FVRQKYFVGY LGERTQSTPG YIFGKRIILF LFLMSVAGIF NYYLIFFFGS DFENYIKTIS TTISPLLLIP
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Arachidonate 5-lipoxygenase-activating protein; FLAP; MK-886-binding protein
基因别名: ALOX5AP; FLAP
Entrez Gene ID: (Human) 241