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Invitrogen
FLI1 Recombinant Rabbit Monoclonal Antibody (K01_1R22)
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FLI1 Antibody (MA563690) in IHC (P)
Immunohistochemistry (Paraffin) analysis of FLI1 in paraffin-embedded Human lung cancer tissue. Samples were incubated with FLI1 recombinant monoclonal (Product # MA563690). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
产品信息
MA563690
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_1R22
抗原
A synthetic peptide of human FLI1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
50mM tris glycine, pH 7.4, with 150mM NaCl, 0.05% BSA, 40% glycerol
内含物
0.01% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
ETS-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes ETS-1, ETS-2, ERG-1, ERG-2, ELK, E74, FLI-1, PU. 1 and PEA3. Members of the ETS gene family exhibit varied pattern of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ewing sarcoma breakpoint region 2; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; Transcription factor ERGB
基因别名: EWSR2; FLI1; SIC-1
UniProt ID: (Human) B4DFV4
Entrez Gene ID: (Human) 2313, (Rat) 315532
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
winged helix/forkhead transcription factor
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
hemostasis
blood circulation
organ morphogenesis
cell differentiation
megakaryocyte development
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
