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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: DQEAEENSLT ETHKCFLETT AYFFMKPKLG EKEVSPNAFF SIWHEFSSDF KDFWKKENKL LLQERVKEAE EVCRQKKGKS LYKIKPRHDS GIKAKISMKT
FMN2, a novel formin homology protein of the cappuccino subfamily, is highly conserved between evolutionarily diverse vertebrates. FMN2 bears a high degree of similarity to formin-1 which is the founding member of formin homology proteins. FMN2 plays a crucial role in maintenance of the meiotic spindle. The protein is widely expressed in human fetal brain, adult whole brain, hypothalamus, retina, pancreatic islet and germinal-center B cells. Pathological role of the protein is identified in various tumors like parathyloid tumor, glioblastoma, retinoblastoma and chondrosarcoma. FMN2 mutations are often a cause of unexplained infertility in women. The gene encoding for human FMN2 is localized in the chromosomal region 1q43.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RP11-90L13.1; unnamed protein product
UniProt ID: (Human) Q9NZ56
Entrez Gene ID: (Human) 56776