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Invitrogen
FMNL3 Polyclonal Antibody
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产品信息
PA5-54720
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LDLENENMMR VAELEKQLLQ REKELESIKE TYENTSHQVH TLRRLIKEKE EAFQRRCHLE PNVRGLESVD SEALARVGPA ELSEGMPPSD LDLLAPAPPP EEVLPLPPPP APPLPPPPPP LPDKCP
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.
靶标信息
FMNL3, also known as Formin-like protein 3, is a 1028 amino acid containing protein involved in immunity or defense. This developmental protein is implicated in polarity control, invasion, migration, or metastasis through regulation of the Rho-related signaling pathway. It belongs to the formin homology family and contains a FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain and has high sequence identity to the mouse Wbp3 protein. Two different isoforms have been described. Itis suspectedbe involved in gastric cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Formin homology 2 domain-containing protein 3; formin-like 3; Formin-like protein 3; WBP-3; WW domain binding protein 3; WW domain-binding protein 3
基因别名: FHOD3; FMNL3; FRL2; KIAA2014; WBP-3; WBP3
UniProt ID: (Human) Q8IVF7
Entrez Gene ID: (Human) 91010
