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Abnova
FNDC4 Polyclonal Antibody, MaxPab™
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产品信息
H00064838-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FNDC4 (NP_073734.1, 1 a.a. approximately 234 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPSGCHSSPP SGLRGDMASL VPLSPYLSPT VLLLVSCDLG FVRADRPPSP VNVTVTHLRA NSATVSWDVP EGNIVIGYSI SQQRQNGPGQ RVIREVNTTT RACALWGLAE DSDYTVQVRS IGLRGESPPG PRVHFRTLKG SDRLPSNSSS PGDITVEGLD GERPLQTGEV VIIVVVLLMW AAVIGLFCRQ YDIIKDNDSN NNPKEKGKGP EQSPQGRPVG TRQKKSPSIN TIDV
靶标信息
Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fibronectin type III domain-containing protein 4; Fibronectin type III repeat-containing protein 1
基因别名: FNDC4; FRCP1; UNQ6389/PRO21134
UniProt ID: (Human) Q9H6D8
Entrez Gene ID: (Human) 64838
