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Invitrogen
FNDC4 Monoclonal Antibody (OTI1B7)
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FNDC4 Antibody (MA5-26140) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human colon tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a FNDC4 monoclonal antibody (Product # MA5-26140).
产品信息
MA5-26140
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1B7
抗原
Full length human recombinant protein of FNDC4 produced in HEK293T cell
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fibronectin type III domain-containing protein 4; Fibronectin type III repeat-containing protein 1
基因别名: FNDC4; FRCP1; UNQ6389/PRO21134
UniProt ID: (Human) Q9H6D8
Entrez Gene ID: (Human) 64838
